PEPFAR is the President’s Emergency Plan for AIDS Relief, the U.S. Government initiative to help save and improve the lives of those suffering from or at risk of contracting HIV/AIDS around the world. Started in 2003, PEPFAR is the largest commitment by any nation in history to combat a single disease internationally, and its investments also help build strong health systems to prevent and alleviate suffering from other diseases. PEPFAR is driven by a shared responsibility among donor and partner nations to make smart investments to save lives.

With U.S. leadership and support, tremendous progress has been made in the fight against global AIDS. PEPFAR had directly supported life-saving antiretroviral treatment for more than 5.1 million men, women, and children as of September 2012. PEPFAR directly supported more than 15 million people with care and support programs last year, including more than 6 million orphans and vulnerable children. PEPFAR’s efforts to prevent mother-to-child HIV transmission last year allowed 230,000 babies of HIV-positive mothers to be born HIV-free. PEPFAR is the cornerstone and largest component of the U.S. President’s Global Health Initiative. With a special focus on improving the health of women, newborns and children, the Global Health Initiative’s goal is to save the greatest number of lives by increasing and building upon what works and supporting countries as they work to improve the health of their own people.

For more information about PEPFAR efforts around the world, please visit,, or To read about PEPFAR’s work in Côte d’Ivoire, please select from the menu at left.

What is PEPFAR?  Answers to common questions

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